Helmadol Tab. (Albendazole)
Pharmaceutical Form
Film coated tablets for oral use.
COMPOSITION
One film-coated tablet contains
Albendazole 200 mg.
THERAPEUTIC INDICATIONS
Helmadol is a highly effective antiparasitic
agent of a polyvalent action; the majority of helminthiases may be treated
with this agent:
- nematodosis:
Ascariasis, disease-producing factor – nematode
helminth Ascaris lumbricoidesl;
Trichocefales (whipworm), disease-producing
factor – nematode helminth Trichocephalus trichiurus;
Enterobiasis (pinworms), disease-producing
factor - nematode helminth Enterobius vermicularis;
Ankylostomiasis, disease-producing factors –
Ancylostoma duodenale and Necator americanus; trichinosis, disease-producing
factors – meat porkworms;
Toxocariasis, disease-producing factor -
Toxocara canis, dog parasite;
Strogiloidos (dwarf threadworm), disease-producing
factor – nematode helminth Strongiloides strcoralis,
And also mixed invasions;
- Tissue cestodosis:
Cysticercosis (disease-producing factor - �ysticercus
cellulosus, larval stage of armed tapeworm);
Hydatid disease of liver, lungs, peritoneum,
caused by larval stage of dog tapeworm (Echinococcus granulosus),
Also the drug is applied as an additive agent in
surgical treatment of alveolar echinococcosis.
CONTRAINDICATIONS
- Hypersensitivity to any drug ingredients and
other derivatives of benzimidazole;
- Eye retina pathology;
- Pregnancy;
- Lactation (breast feeding).
ADVERSE EFFECTS
Effects on digestive system: abdominal pains,
nausea, vomiting.
Effects on cardiovascular system: elevation of
blood pressure.
Effects on central nervous system: headache and
dizziness.
Effects on urinary excretion system: changes of
indices of renal function (acute renal impairment).
Dermatologic reactions: itching, skin eruption
and other allergic reactions.
DOSAGE AND ADMINISTRATION
Oral administration during or after meal intake.
Special preparation and diet is not required.
Choose a drug formulation individually depending
on convenience of a drug and tolerance of its compounds.
Determine a dose individually depending on
invasion type, patient’s body weight. The maximum daily dose is 800 mg.
Ascaridiasis, trichocefales: for patients with
body weight of 60 kg and more - 400 mg daily as a single dose or 200 mg 2
times a day; for patients with body weight less than 60 kg – 15 mg/kg daily
divided into two doses.
Enterobiasis: 5 mg/kg of body weight as a single
dose. Repeat the scheme in 14 days.
Strongyloidiasis, ankylostomiasis 10 mg/kg of
body weight daily within 3 days. Repeat the scheme in 14 days.
Trichinosis: 10 mg/kg of body weight daily
divided into two doses within 7-10 days.
Toxocariasis. 10 mg/kg of body weight daily
divided into two doses after meal within 10 days. Repeat the scheme in 14 days
or a month.
Hydatid echinococcosis. Treatment is possible if
laboratory indices are within limits. 10 mg/kg of body weight daily divided
into two or three doses. Therapy course is 3 cycles of 28 days with 14 day’s
interval.
Cysticercosis: 15 mg/kg of body weight daily
divided into three doses. The therapy course is 28-30 days.
OVERDOSAGE
Symptoms: enhancement of adverse reactions is
reported.
Therapy: gastric lavage, prescription of
activated charcoal, symptomatic therapy.
DRUG INTERACTOINS
Dexamethasone and cimetidine increases blood
Albendazole sulfoxide concentration.
PRECAUTIONS
Use Helmadol with cautious in case of hepatic
impairment.
Prior treatment make pregnancy test in women of
childbearing age. Reliable contraception is required during therapy.
Effects on ability to drive and operate with
mechanisms
The drug does not cause changes of patient’s
psychophysical state, does not influence on ability for driving and working
with complicated mechanisms.
PREGNANCY AND LACTATION
Helmadol is contraindicated during pregnancy and
lactation (breast-feeding).
MANUFACTURED FORM
Helmadol 200 mg No 2
Film-coated tablets 200 mg.
2 tablets are in PVC and alfol stripes.
1 stripe with a leaflet is in a carton box.
SALES TERMS
Sold under a prescription.
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