Venodiol
(Diosmin, Hesperidin, Ascorbic acid)




COMPOSITION

Each tablet contains diosmin 450 mg, hesperidin 50 mg, ascorbic acid 100 mg.

THERAPEUTIC INDICATIONS

- Chronic venous insufficiency and of organic nature: sensation of weight in the legs, pain, convulsions, and trophic abnormalities;
- Acute hemorrhoidal attack.

CONTRAINDICATIONS

Hypersensitivity to the drug or any drug compound.

ADVERSE EFFECTS

The adverse reactions caused the drug withdrawal have not been reported. The vegetative reactions (increased weakness, vertigo, a sense of heat and pricking in lower extremities skin) have been observed in several patients only in the first days of Venodiol administration. The onset of these symptoms is not the reason for the drug withdrawal as they disappear spontaneously in 2-3 weeks.

DOSAGE AND ADMINISTRATION

The standard daily dose is an important Venodiol peculiarity, which significantly makes its application easier.
There are two possible methods of administration:
- 1 tablet (500 mg) 2 times a day during meal within the whole therapeutic period;
- 1 tablet 2 times daily for the first 2 weeks, and then 2 tablets (1000 mg) once a day during meal.
The application experience indicates that the duration of Venodiol administration is directly proportional to the severity of disease.
The two-month' course (if necessary repeated usually 2-3 times a year) is enough for the treatment of the primary forms of the chronic venous insufficiency, manifesting by “heavy legs” syndrome.
In more severe cases when pain, spastic, edematic syndrome is prevailed Venodiol administration should be continued within 3-4 months.
The treatment of trophic venous ulcers may require more protracted course of 6 months and more.
In acute hemorrhoidal attack: 6 tablets daily for the first 4 days, then 4 tablets a day for the next 3 days.
When prescribed Venodiol it is necessary to remember that there is no the drug addiction.

DRUG INTERACTIONS

The drug interactions have not been described.

PREGNANCY AND LACTATION

To date there is no data on adverse effects associated with Venodiol application in pregnant women.
The breast-feeding is not recommended during treatment with Venodiol, since the data on penetration of the drug active substances in the human milk is not available.
Teratogenic effects have not been established in experimental studies.

10 tablets are in PVC and aluminum foil blisters. 3 blisters with a leaflet are in a carton box

Cardiovascular System

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