COMPOSITION

5 g of granules contain:
Calcium-magnesium inositohexaphosphate 125 mg;
Calcium gluconate 375 mg;
Vitamin D2 3000 IU.

THERAPEUTIC INDICATIONS

- Prophylaxy and treatment of rachitism: disorders of calcium metabolism accompanied with osteopathy, spasmophilia, disorders of bone formation and dental eruption, growth retention in period of intensive development of the body;
- Prophylaxy of osteoporosis of different genesis;
- Conditions during which demand in vitamin D and calcium increases:
Breast-feeding children or children with inadequate fresh air intake;
Bottle-feeding children with vitamin D deficiency;
Malabsorption syndrome, chronic diarrhea, gastrectomy;
Neurasthenia;
Steatorrhea;
- Patients facing therapy with hormones, anticonvulsants, immune suppressors, aluminium-containing antacids, diuretics.

CONTRAINDICATIONS

- Hypercalcemia;
- Hypervitaminosis D;
- Hyperphosphatasemia;
- Hyperparathyroidism.

ADVERSE EFFECTS

The drug is generally well tolerated.
During long-term use hypercalcemia is possible.

DOSAGE AND ADMINISTRATION

D-Calcin is taken orally.
Prophylaxy of osteoporosis: 1000-2000 IU daily (1/4-1/2 of measuring cup).
Prophylaxy of rachitism and osteomalation: 400 IU daily (1 coffee spoon).
Treatment of vitamin D2 nutrition deficiency, rachitism and osteomalation: in adults 1000-2000 IU daily (1/4-1/2 of measuring cup), in children 1000-4000 IU daily (1/4-1 of measuring cup).
Treatment should last over several months. After completing treatment course if necessary can be followed by taking preventive doses of vitamin D (400 IU) for adults and children.
Osteomalation in patients with long-term intake of anticonvulsants: in adults 1000-4000 IU (1/4-1 of measuring cup) daily, in children 1000 IU (1/4 of measuring cup) daily.

DRUG INTERACTIONS

Vitamin A, tokoferol, hexuronic acid, pantothenic acid, tiamin, riboflavin decrease the drug action. In case of vitamin D hypervitaminosis the potantiation of cardiac glycoside and risk of arrhythmia is possible. By the action of barbiturates (including phenobarbital), primidon, phenytoin demand of ergocalciferol can increase (increase the speed of metabolism). In case of simultaneous intake with sodium fluoride interval should be not less than 2 hours. The simultaneous administration with other polyvitaminic complexes containing calcium and vitamin D should be avoided.

PRAGNANCY AND LACTATION

During the pregnancy intake of high doses of vitamin В is not recommended. During breast–feeding the product should be given with caution.

MANUFACTURED FORM

Granules 75 g. in plastic bottle with dose-measuring cup with leaflet in carton box.