COMPOSITION

Each ampoule contains:
Dissodium adenosine triphosphate trihydrate 10 mg
Cocarboxylase 50 mg
Cyanocobalamin 0.5 mg
Nicotinamide 20 mg

THERAPEUTIC INDICATIONS

- Neuritis, neuropathy (in diabetes mellitus, pernicious anemia and etc.);
- Neuralgia of various genesis;
- Myalgia, ischialgia;
- Lumbago, radiculitis;
- Bursitis, tendinitis;
- Ischemic cardiac disease, myocarditis, myocardiopathy.

CONTRAINDICATIONS

- Hypersensitivity to any of the drug component.
- Acute period of myocardial infarction.
- Hypersensitivity, hypercoagulation (including acute thrombosis), erythremia, erythrocytosis, severe arterial hypertension, arterial hypotension, acute myocardial infarction, inflammatory disease of lungs.

ADVERSE EFFECTS

Headache, vertigo, tachycardia, allergic reactions (urticaria). IM injection may cause hyperemia, pruritus and edema in the site of introduction. The drug is discontinued when apparent adverse effects appear.

DOSAGE AND ADMINISTRATION

1-2 ampoules of Cocarnit are IM injected once daily.
The duration of therapy and initiation of refresher course of treatment depends on kind and severity of disease.

DRUG INTERACTIONS

Cocarboxylase enhances a cardiotonic action of cardiac glycosides.

PREGNANCY AND LACTATION

Cocarnit should be applied during pregnancy only if expected benefit for mother justifies potential risk for fetus.
Breast-feeding should be discontinued during drug therapy.

MANUFACTURED FORM

Lyophilized powder for injections in glass ampoules. 3 ampoules complete with a solvent (3 (2 ml) ampoules of 0.5% lidocaine hydrochloride) are in strips in a carton box with an annotation-insert.