Amlipin Tablet
(Amlodipin - Lisinopril)




COMPOSITION

Each film coated tablet contains amlodipine (as besilate) 5 mg, lisinopril (as dihydrate) 5 mg.

THERAPEUTIC INDICATIONS

- Arterial hypertension;
- Ischemic heart disease (stable angina, Prinzmetal's angina);
- Chronic cardiac insufficiency (as a part of complex therapy);
- Diabetic nephropathy.

CONTRAINDICATIONS

- Increased sensitivity to any component of a preparation or to other derivatives of dihydropyridine;
- Angioneurotic edema in the anamnesis, including connected with application of others inhibitors APC;
- Hemodynamically significant stenosis of an aortic or mitral valve;
- The expressed arterial hypotension;
- Cardiogenic shock;
- Pregnancy and the period of a lactation;
- Children's age.

ADVERSE EFFECTS

Side effects are usually poorly expressed and have passing character, discontinuation of theatment is required in rare cases;
Most often meet: a headache, dry cough and dizziness;
Are possible: weakness, a diarrhea, a nausea, vomiting, orthostatic hypotension, a skin itch, a skin rash, a hypostasis of foots' ankles, reddening of face skin, a pain in breast;
Frequency of other side-effects is less than 1%;
At the increased sensitivity development of angioneurotic edema is possible.

DOSAGE AND ADMINISTRATION

Amlipin should be administered orally 1 tablet once a day irrespective of meals. If necessary the daily dose can be increased to 2 tablets.

DRUG INTERACTIONS

Simultaneous reception with potassium-sparing diuretic (spironolactone, amiloride, triamteren), potassium and potassium containing means in order to prevent the development of hyperpotassemia demands extra care, mainly, at the reduced function of kidneys. Prescribed after the careful estimation of advantage and risk, conducting the regular control of potassium level in blood and kidney function.

MANUFACTURED FORM

Film coated tablets. 10 tablets in blister. 3 blisters in carton box with enclosed leaflet.

Cardiovascular System

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